<?xml version="1.0" encoding="US-ASCII"?>

<!--XBRL Document Created with WebFilings-->

<xsd:schema xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:jsda="http://www.jonessoda.com/20111231" xmlns:xsd="http://www.w3.org/2001/XMLSchema" xmlns:nonnum="http://www.xbrl.org/dtr/type/non-numeric" targetNamespace="http://www.jonessoda.com/20111231" elementFormDefault="qualified" attributeFormDefault="unqualified"><xsd:import schemaLocation="http://xbrl.fasb.org/us-gaap/2011/elts/us-gaap-2011-01-31.xsd" namespace="http://fasb.org/us-gaap/2011-01-31"/><xsd:import schemaLocation="http://xbrl.fasb.org/us-gaap/2011/elts/us-roles-2011-01-31.xsd" namespace="http://fasb.org/us-roles/2011-01-31"/><xsd:import schemaLocation="http://xbrl.fasb.org/us-gaap/2011/elts/us-types-2011-01-31.xsd" namespace="http://fasb.org/us-types/2011-01-31"/><xsd:import schemaLocation="http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd" namespace="http://www.xbrl.org/2003/instance"/><xsd:import schemaLocation="http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" namespace="http://www.xbrl.org/2003/linkbase"/><xsd:import schemaLocation="http://www.xbrl.org/lrr/arcrole/factExplanatory-2009-12-16.xsd" namespace="http://www.xbrl.org/2009/arcrole/fact-explanatoryFact"/><xsd:import schemaLocation="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd" namespace="http://www.xbrl.org/2009/role/negated"/><xsd:import schemaLocation="http://www.xbrl.org/lrr/role/net-2009-12-16.xsd" namespace="http://www.xbrl.org/2009/role/net"/><xsd:import schemaLocation="http://www.xbrl.org/dtr/type/nonNumeric-2009-12-16.xsd" namespace="http://www.xbrl.org/dtr/type/non-numeric"/><xsd:import schemaLocation="http://www.xbrl.org/dtr/type/numeric-2009-12-16.xsd" namespace="http://www.xbrl.org/dtr/type/numeric"/><xsd:import schemaLocation="http://www.xbrl.org/2005/xbrldt-2005.xsd" namespace="http://xbrl.org/2005/xbrldt"/><xsd:import schemaLocation="http://xbrl.sec.gov/country/2011/country-2011-01-31.xsd" namespace="http://xbrl.sec.gov/country/2011-01-31"/><xsd:import schemaLocation="http://xbrl.sec.gov/currency/2011/currency-2011-01-31.xsd" namespace="http://xbrl.sec.gov/currency/2011-01-31"/><xsd:import schemaLocation="http://xbrl.sec.gov/dei/2011/dei-2011-01-31.xsd" namespace="http://xbrl.sec.gov/dei/2011-01-31"/><xsd:import schemaLocation="http://xbrl.sec.gov/exch/2011/exch-2011-01-31.xsd" namespace="http://xbrl.sec.gov/exch/2011-01-31"/><xsd:import schemaLocation="http://xbrl.sec.gov/invest/2011/invest-2011-01-31.xsd" namespace="http://xbrl.sec.gov/invest/2011-01-31"/><xsd:import schemaLocation="http://xbrl.sec.gov/naics/2011/naics-2011-01-31.xsd" namespace="http://xbrl.sec.gov/naics/2011-01-31"/><xsd:import schemaLocation="http://xbrl.sec.gov/sic/2011/sic-2011-01-31.xsd" namespace="http://xbrl.sec.gov/sic/2011-01-31"/><xsd:import schemaLocation="http://xbrl.sec.gov/stpr/2011/stpr-2011-01-31.xsd" namespace="http://xbrl.sec.gov/stpr/2011-01-31"/><xsd:annotation><xsd:appinfo><link:linkbaseRef xlink:role="http://www.xbrl.org/2003/role/calculationLinkbaseRef" xlink:type="simple" xlink:href="jsda-20111231_cal.xml" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase"/><link:linkbaseRef xlink:role="http://www.xbrl.org/2003/role/definitionLinkbaseRef" xlink:type="simple" xlink:href="jsda-20111231_def.xml" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase"/><link:linkbaseRef xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:type="simple" xlink:href="jsda-20111231_lab.xml" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase"/><link:linkbaseRef xlink:role="http://www.xbrl.org/2003/role/presentationLinkbaseRef" xlink:type="simple" xlink:href="jsda-20111231_pre.xml" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase"/><link:roleType id="AccruedExpenses" roleURI="http://www.jonessoda.com/role/AccruedExpenses"><link:definition>2104100 - Disclosure - Accrued Expenses</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="CapitalLease" roleURI="http://www.jonessoda.com/role/CapitalLease"><link:definition>2106100 - Disclosure - Capital Lease</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="CommitmentsAndContingencies" roleURI="http://www.jonessoda.com/role/CommitmentsAndContingencies"><link:definition>2111100 - Disclosure - Commitments and Contingencies</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="ConsolidatedBalanceSheets" roleURI="http://www.jonessoda.com/role/ConsolidatedBalanceSheets"><link:definition>1001000 - Statement - Consolidated Balance Sheets</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="ConsolidatedBalanceSheetsParenthetical" roleURI="http://www.jonessoda.com/role/ConsolidatedBalanceSheetsParenthetical"><link:definition>1001500 - Statement - Consolidated Balance Sheets (Parenthetical)</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="ConsolidatedStatementsOfCashFlows" roleURI="http://www.jonessoda.com/role/ConsolidatedStatementsOfCashFlows"><link:definition>1005000 - Statement - Consolidated Statements of Cash Flows</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="ConsolidatedStatementsOfComprehensiveLoss" roleURI="http://www.jonessoda.com/role/ConsolidatedStatementsOfComprehensiveLoss"><link:definition>1003000 - Statement - Consolidated Statements of Comprehensive Loss</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="ConsolidatedStatementsOfOperations" roleURI="http://www.jonessoda.com/role/ConsolidatedStatementsOfOperations"><link:definition>1002000 - Statement - Consolidated Statements of Operations</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="ConsolidatedStatementsOfShareholdersEquity" roleURI="http://www.jonessoda.com/role/ConsolidatedStatementsOfShareholdersEquity"><link:definition>1004000 - Statement - Consolidated Statements of Shareholders' Equity</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="ConsolidatedStatementsOfShareholdersEquityParenthetical" roleURI="http://www.jonessoda.com/role/ConsolidatedStatementsOfShareholdersEquityParenthetical"><link:definition>1004500 - Statement - Consolidated Statements of Shareholders' Equity (Parenthetical)</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="DocumentAndEntityInformation" roleURI="http://www.jonessoda.com/role/DocumentAndEntityInformation"><link:definition>0001000 - Document - Document and Entity Information</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="Employee401KPlan" roleURI="http://www.jonessoda.com/role/Employee401KPlan"><link:definition>2110100 - Disclosure - Employee 401(k) Plan</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="EquityFinancing" roleURI="http://www.jonessoda.com/role/EquityFinancing"><link:definition>2108100 - Disclosure - Equity Financing</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="FixedAssets" roleURI="http://www.jonessoda.com/role/FixedAssets"><link:definition>2103100 - Disclosure - Fixed Assets</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="IncomeTaxes" roleURI="http://www.jonessoda.com/role/IncomeTaxes"><link:definition>2113100 - Disclosure - Income Taxes</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="Inventory" roleURI="http://www.jonessoda.com/role/Inventory"><link:definition>2102100 - Disclosure - Inventory</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="LeaseObligations" roleURI="http://www.jonessoda.com/role/LeaseObligations"><link:definition>2107100 - Disclosure - Lease Obligations</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="LineOfCredit" roleURI="http://www.jonessoda.com/role/LineOfCredit"><link:definition>2105100 - Disclosure - Line of Credit</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="NatureOfOperationsAndSummaryOfSignificantAccountingPolicies" roleURI="http://www.jonessoda.com/role/NatureOfOperationsAndSummaryOfSignificantAccountingPolicies"><link:definition>2101100 - Disclosure - Nature of Operations and Summary of Significant Accounting Policies</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="SegmentInformation" roleURI="http://www.jonessoda.com/role/SegmentInformation"><link:definition>2115100 - Disclosure - Segment Information</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="SelectedQuarterlyFinancialInformation" roleURI="http://www.jonessoda.com/role/SelectedQuarterlyFinancialInformation"><link:definition>2117100 - Disclosure - Selected Quarterly Financial Information</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="ShareholdersEquity" roleURI="http://www.jonessoda.com/role/ShareholdersEquity"><link:definition>2109100 - Disclosure - Shareholders' Equity</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="SubsequentEvents" roleURI="http://www.jonessoda.com/role/SubsequentEvents"><link:definition>2116100 - Disclosure - Subsequent Events</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType><link:roleType id="WriteDownOfExcessGabaInventory" roleURI="http://www.jonessoda.com/role/WriteDownOfExcessGabaInventory"><link:definition>2112100 - Disclosure - Write-down of Excess GABA Inventory</link:definition><link:usedOn>link:presentationLink</link:usedOn><link:usedOn>link:calculationLink</link:usedOn><link:usedOn>link:definitionLink</link:usedOn></link:roleType></xsd:appinfo></xsd:annotation><xsd:element type="xbrli:stringItemType" id="jsda_CashPaidReceivedDuringPeriodAbstract" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" name="CashPaidReceivedDuringPeriodAbstract" abstract="true"/><xsd:element type="xbrli:stringItemType" id="jsda_DocumentAndEntityInformationAbstract" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" name="DocumentAndEntityInformationAbstract" abstract="true"/><xsd:element type="nonnum:textBlockItemType" id="jsda_EquityFinancingNoteDisclosureTextBlock" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" name="EquityFinancingNoteDisclosureTextBlock"/><xsd:element type="xbrli:monetaryItemType" id="jsda_IncreaseDecreaseInDeferredRentPayable" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" name="IncreaseDecreaseInDeferredRentPayable" xbrli:balance="debit"/><xsd:element type="xbrli:stringItemType" id="jsda_LeaseObligationsAbstract" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" name="LeaseObligationsAbstract" abstract="true"/><xsd:element type="nonnum:textBlockItemType" id="jsda_LeaseObligationsTextBlock" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" name="LeaseObligationsTextBlock"/><xsd:element type="xbrli:stringItemType" id="jsda_LineOfCreditAbstract" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" name="LineOfCreditAbstract" abstract="true"/><xsd:element type="xbrli:monetaryItemType" id="jsda_NonCashPaymentsOfStockIssuanceCosts" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" name="NonCashPaymentsOfStockIssuanceCosts" xbrli:balance="credit"/><xsd:element type="xbrli:monetaryItemType" id="jsda_ProceedsFromCapitalLeaseObligations" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" name="ProceedsFromCapitalLeaseObligations" xbrli:balance="debit"/><xsd:element type="xbrli:monetaryItemType" id="jsda_ProceedsFromRedemptionOfRestrictedCertificatesOfDeposit" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" name="ProceedsFromRedemptionOfRestrictedCertificatesOfDeposit" xbrli:balance="debit"/><xsd:element type="xbrli:sharesItemType" id="jsda_WeightedAverageNumberOfSharesBasicAndDilutedOutstanding" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" name="WeightedAverageNumberOfSharesBasicAndDilutedOutstanding"/><xsd:element type="xbrli:stringItemType" id="jsda_WriteDownOfExcessGabaInventoryAbstract" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" name="WriteDownOfExcessGabaInventoryAbstract" abstract="true"/><xsd:element type="xbrli:monetaryItemType" id="jsda_WriteDownOfExcessInventory" xbrli:periodType="duration" substitutionGroup="xbrli:item" nillable="true" name="WriteDownOfExcessInventory" xbrli:balance="debit"/></xsd:schema>